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Research Article

Academia Journal of Biotechnology 5(12): 243-247, December 2017
DOI: 10.15413/ajb.2017.0246
ISSN: 2315-7747
2017 Academia Publishing

Abstract


A case and literature review of Relapsing polychondritis
 

Accepted 11th October, 2017
 
Anna Zhou1, Xindi Li2, Lin Zhao2, Yonghong Liu2, Heng Zhou2, Huabing Wang2, Tian Song2 and Xinghu Zhang2*

1Beijing Children hospital Capital Medical University
2Department of Neurology, Beijing Tiantan Hospital Capital Medical University, No. 6 Tiantanxili Dongcheng District, Beijing, China.

 

This study aims to describe the clinical manifests, CSF features and brain MRI characters of patients with relapsing polychondritis (RP) and central nervous system (CNS) involvement presented as encephalitis. Seven cases with RP and CNS involvement were enrolled from 2011 to 2015. RP was diagnosed upon the modified McAdam criteria and CNS dysfunction secondary to RP decided by clinical manifests, CSF analysis and brain MRI. Of the seven (7) cases, three (3) confirmed RP, while four (4) were probable. All of the RP patients with CNS involvement were presented as encephalitis. The common clinical features of CNS involvement were fever and headache, while brain MRI findings were in diversity. The CNS symptoms were relieved after steroid. CNS involvement in RP has no specific findings both in symptoms and brain MRI findings. When one patient presented with encephalitis has extra-CNS manifestations such as eye and ear abnormalities, CNS involvement of RP should be suspected.

Keywords: Relapsing polychondritis (RP), central nervous system (CNS), encephalitis.

 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:
Zhou A, Li X, Zhao L, Liu Y, Zhou H, Wang H, Song T, Zhang X (2017). A case and literature review of Relapsing polychondritis. Acad. J. Biotechnol. 5(12): 243-247.

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