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Research Article

Academia Journal of Scientific Research 5(11): 587-590, November 2017
DOI: 10.15413/ajsr.2017.0430
ISSN: 2315-7712
2017 Academia Publishing 

Abstract

 


Genetic testing in clinical practice: An ethical perspective
 

Accepted 9th October, 2017

 
Kinan Mokbel1, Kefah Mokbel1*

1The London Breast Institute, The Princess Grace Hospital, London, UK.

The complexity of interpreting the results of genome-scale testing and the interplay of ethical principles present a challenge to the medical establishment regarding genomic information disclosure. This article focuses on the most problematic ethical issues regarding the disclosure of genetic information to biological relatives who might benefit from such vital information for their health or future well-being. The justification for concealing an individual’s genetic information and the rationale behind disclosing these valuable data are elucidated. Furthermore, this article analyses various societal factors and the different ways in which individuals understand concepts of family and self that might hinder disclosure and how not discussing these topics and understanding the social and cultural differences at the very beginning of genetic counselling complicates the decision. As the partial overlap of ethical principles might conceal significant moral nuances, genetics professionals need to make decisions on a case-by-case basis and use their judgement by weighing up the benefits against potential risks to make a rational yet realistic decision. Detailed genetic counselling to encourage the patients to communicate with their at-risk family members before the genetic testing and striking a balance between the potential advantages and the possible risks for each case are essential.

Keywords: Genome-scale testing, ethical principles, genetic counselling
 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article as:
Mokbel K, Mokbel K (2017). Genetic testing in clinical practice: An ethical perspective. Acad. J. Sci. Res. 5(11): 587-590.

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