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Research Article

Academia Journal of Microbiology Research 2(2): 028-032, December 2014
DOI: http://dx.doi.org/10.15413/ajmr.2014.0103
ISSN: 2315-7771
2014 Academia Publishing


 

Abstract

 

Determination of minimum inhibitory concentrations of 2-(2-nitrovinyl) furan
 

Accepted 14th September, 2014

 

Alabi K.A1*, and Hassan GF2
1Department of Chemical sciences, Fountain University, P.M.B. 4491, Oke-Osun, Osogbo. Nigeria.
2Department of Crop, soil and Pest Management, Federal University of Technology, Akure. Nigeria.
Corresponding author: qasimade@gmail.com, Mobile: 08034705605.

 

The minimum inhibitory concentration of the synthesized compound 2-(2-Nitrovinyl) Furan was determined due to its potency towards some pathogens. The compound inhibited all the fungal isolates used in the research at concentrations of 510-1 mg/ml and 510-2 mg/ml respectively. It was also active towards Rhizoctonia solani and Drechslera oryzae at concentration of 510-3 mg/ml but only D. oryzae at concentration of 510-2 mg/ml. The activity of the compound diminished with decrease in concentration. The inhibition zones for 2-(2-Nitrovinyl) Furan are 15 mm (Bacillus cereus), 17.5 mm (Shigella dysenteriae), 19 mm (Bacillus subtilis), 19 mm (Pseudomonas syringae), 19 mm (Pseudomonas fluorescens), 20 mm (Staphylococus epidemidis), 20 mm (Xanthomonas manihoti), 19 mm (Candida albican) and 20 mm (Geotrichum albidus) respectively. The results clearly indicated that among the concentrations (510-1 to 510-6 mg/ml) used for the study, the MIC of 2- (2-Nitrovinyl) Furan at 510-1 mg/ml and 510-2 mg/ml were the most effective concentrations and as well the minimum inhibitory concentrations. 2- (2-Nitrovinyl) Furan is a very good antimicrobial agent that would be very useful in medical and agrochemical industries.

Key words: 2-(2-Nitrovinyl) furan, minimum inhibitory concentration, pathogens, potency.
 

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

Cite this article as:
Alabi KA, Hassan GF (2014). Determination of minimum inhibitory concentrations of 2-(2-nitrovinyl) furan. Acad. J. Microbiol. Res. 2(2):028-032.

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